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New York Jets vs Buffalo Bills Preview, Predictions, and Betting Odds – NFL 2025-26 Season Week 2

Eric Divakaran
American Football / NFL
14/09/2025 – 18:00
New York Jets
VS
18:00
14/09/2025
Buffalo Bills
Odds updated on September 11, 2025 at 9:49 pm

New York Jets vs Buffalo Bills Preview, Predictions, and Betting Odds – NFL 2025-26 Season Week 2

The Buffalo Bills visit the New York Jets in an AFC East showdown on September 14, 2025. Buffalo rides high after a miraculous 41-40 comeback win over the Ravens, led by Josh Allen’s MVP-caliber heroics. The Jets on the other hand, stung by 34-32 loss to the Steelers, seek redemption under new coach Aaron Glenn.

The rivalry will test Justin FIelds’ dual-threat ability against Buffalo’s stout defense. Expect fireworks as both teams vie for early divisional edge.

Recommended BetsFanDuelBetMGM
Josh Allen to throw for over 231.5-114-115
Total Touchdowns Under 5.5 -152-155
Buffalo Bills to win the game-310-325
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Analysis and Rationale

Josh Allen is likely to exceed 231.5 passing yards against the New York Jets as in Week 1, Allen threw for 394 yards against a tougher Ravens defense. The Jets’ secondary, despite Sauce Gardner, allowed 218 yards to Aaron Rodgers. Allen’s 7.7 passing yards per attempt in 2024 and Buffalo’s aggressive passing game makes us believe that this is a safe bet.

For our second bet, the Jets vs Bills game is likely to stay under 5.5 total touchdowns due to the Jets’ stout defense, led by Sauce Gardner, which held the Steelers to 34 points (4 TDs) in Week 1 but forced turnovers and limited efficiency. Buffalo’s offense exploded for 41 points against the Ravens, but we doubt that it will be case again this time. While it is not a guaranteed bet, and the Bills have the capability to explode, we believe that this is a safe bet.

The Buffalo Bills are favored to win against the New York Jets as Josh Allen’s Week 1 heroics (394 yards, 2 TDs in a 41-40 comeback vs Ravens) could exploit the Jets’ secondary, which allowed 244 passing yards to Aaron Rodgers. Justin Fields’ dual-threat ability showed a lot of promise, but New York’s loss in Week 1 exposed their defensive lapses. So we believe that it’s safe to bet on the Bills to win the game.

New York Jets vs Buffalo Bills Preview

The Buffalo Bills (1-0) face the New York Jets (0-1) in an AFC East clash on September 14, 2025, at MetLife Stadium, airing at 1:00 p.m. ET on CBS. Fresh off a 41-40 comeback against the Ravens, Josh Allen leads Buffalo against a Jets team reeling from a 34-32 loss to the Steelers.

New York Jets Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the New York Jets, according to BetMGM

Over/Under BetsOverUnder
Justin Field Passing Touchdown191.5 (-115)191.5 (-115)
Garrett Wilson Receiving Yards60.5 (-115)60.5 (-115)
Breece Hall Rushing Yards56.5 (-115)56.5 (-115)

New York Jets Best Player Bets

Below are some of the best player bets for the New York Jets, according to BetMGM

  • Justin Field to have over 0.5 passing touchdowns: -220
  • Breece Hall to have over 12.5 rushing attempts: -140
  • Nick Folk to have under 1.5 field goals: -175
  • Justin Field to have under 0.5 interceptions: -150
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Buffalo Bills Best Bets – Over/Under and Player Bets

Here are over/under and best player bets for the Buffalo Bills, according to BetMGM

Over/Under BetsOverUnder
Josh Allen Passing Yards231.5 (-115)231.5 (-115)
Keon Coleman Receiving Yards46.5 (-115)46.5 (-115)
James Cook56.5 (-118)56.5 (-115)

Buffalo Bills Best Player Bets

Below are some of the best player bets for the Buffalo Bills, according to BetMGM

  • Josh Allen to throw under 0.5 interceptions: -135
  • Josh Allen to have under 1.5 touchdowns: -130
  • James Cook to have under 13.5 rushing attempts: -125
  • Josh Allen to have under 7.5 rushing attempts: -150
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Jets vs Bills Prediction for the 2025-26 Season

The Buffalo Bills are predicted to defeat the New York Jets in Week 2 because of Josh Allen’s MVP performance in Week 1, which could overpower the Jets’ defense, which allowed 4 TDs to Aaron Rodgers. Justin Fields may manage to keep the game close but ultimately, Buffalo’s offense should be able to overwhelm the Jets.

Prediction: Buffalo Bills to win the game

Jets vs Bills Betting Odds and Spread

The spread and the moneyline shows that the Buffalo Bills are the clear favorites and should be able to take down the New York Jets, according to BetMGM

TeamsSpreadTotal PointsMoneyline
Buffalo Bills-6.5 (-110)46.5 (-110)-325
New York Jets+6.5 (-110)46.5 (-110)+260

(According to BetMGM: BetMGM offers exclusive promo codes, bonus deals and accurate odds for users upon signing up. Use BetMGM to ace your betting game in all sports!)

When and where is the Jets vs Bills game in Week 2?

The New York Jets host the Buffalo Bills on September 14, 2025, at MetLife Stadium.

What are the BetMGM betting odds for the Jets vs Bills game?

Bills are -6.5 favorites with a moneyline of Bills -325, and Jets at +260.

What are key player prop bets to look out for from BetMGM, for the Jets vs Bills game?

Josh Allen Over 231.5 Passing Yards: -115
Justin Fields Over 0.5 Passing TDs: -220
Breece Hall Over 12.5 Rushing Attempts: -140

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I cover the National Football League and things cannot get better than that. I always dreamed to play football or basketball professionally since I’m built like a Running Back. But now that I can’t, since I’m technically in the “Unc” age, I thought why not pick a career in sports industry? So here I am, doing what I love, and hoping that the Commanders win the Super Bowl. I give love to players when it’s due, but can be critical about their performances at the same time. Enough about me, now let my articles do all the talking. 

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